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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be8a2762162d5c5e0d11ab0f1359d62b46bac1e9931943c7a3a7fd0a5d082cb9' 
  AND token = 'aDcdUP4tj0xFrEsYY5d9ad4YUPn7T4Csb22KYhKq/ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}