SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '431f38ff9f178b1706c1f198367db1e7bc235170e11ff836f69aac89d2e7d990' 
  AND token = 'YP7m3B3QwwzWLsGNr5BtEdd5DtVjFiHfVD54ISJxyNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}