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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ff06d372071b51e740cee21812b0c24c989a2bd79fef1b5a876f2f0d52d2ce1' 
  AND token = 'r1IRyI9+7yAcT3sTbVAdf1TmtGkyZQWpr5hdqIJvzVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}