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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7d76f342b42421b9e487a3c2d0d0b563c86b5e9c02956988295f9d9f91e27e9' 
  AND token = 'Lr3iN0ATQUVyBWhRuhUTuycDak2/at7ZUARt6R08Ct8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}