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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a0176c643c93b5359980a73f44e2cb00498c211c3f4a2cd9140ca8e0c78b9c1' 
  AND token = 'AJ+X8KOuSCMbWIjSpL9FVBB1I3p0h4F9HdoXPgLvQt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}