SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc2da36b378bd320053c91b643738b4dfa9ab4db63c00bf4c2ed9ca25c0d4759' 
  AND token = 'VdUMlRQqa+aaAK05fruB4LowxJTkB7DMOyLAs84JoCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}