SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c57778ae74d6108c862bae2d1605b801642f37e969735f8451d4625799f307e' 
  AND token = '5b7KFop8VoZTPBb7a/m/OMAdrzVm4v2ksFqEKD2aWTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}