SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8fdbca4d11a84b6b069ec454334f7ccf34b2d2649a4a677318f07f40d07a6f' 
  AND token = '2YGOZybr1byH1X+P7RddTEJRBaF7TwtqeCjSCukIRdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}