SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3f49ca944d64a6bac4242bd4ca31261abc72fe85239d0c3327223d2bb22680f' 
  AND token = 'cwhLe2ghOEha2QjveGCBSwZhH8LgxOAJQy1tbERr3A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}