SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abc33bc9f22f5b13fb0a66ab0b73ddeda938bf1c55fdd4d4e429a1145aa0337f' 
  AND token = 'DzIEXdND4El9FR0+oE2K2X9zyAAGaAFvYupLf/uKIDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}