SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bd80b4b6f3166d61f3434ee489e44171305591ae2668920e1dbf5849e8e2324' 
  AND token = '+Wn3WCaHv6na1Vrss5CQIY6KVoC46c0Ts/bvvd6ZMAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}