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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55fd268fe296e4df09626442fe528fd8cdfb07bc1563cfd4f76bea33fcdf1a32' 
  AND token = 'GVa0vm8i1BHB0hVFadHqDSG7CmrI9F01NFqfJsaYBHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}