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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d068b4e1acd050e134bb130a8753bb6bd9e2f7ee37bcc49c362b3e353411164' 
  AND token = 'it2V9QNvTt1yOVFvpg+Ajb+qjuS6ylt3nHpAxXuH8dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}