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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d3ad32ce28ddf9ad1f61222d139a6b6fc69804f717c456e2d21466bd21028e5' 
  AND token = 'oQGkh3uxaOh2GXHBVAUfitsuFQBbAbOxMg/9vXEXWNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}