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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df9e83e82ba0a7674efb1df09ca751b7bd56815ccc4e2054f0a8f39853e43cf' 
  AND token = 'eeN7WG9RUAHIlcllTf80Mzbyet6HpEZ+AVU8zXWoSLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}