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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2324a6f4ffe288b6a5f22a8a17fd70d51b9a71a96899b0114c906e84eac2c7a7' 
  AND token = 'QoxMOY56Xo3HDe2VWrZlMEazzHDrJE4x37mjZ0PQoy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}