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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9b5b2ab646054845f2bf663b9e0533f55c3a21d3c1a3cb251d5ed2c1d6c4153' 
  AND token = 'CKNiUdynxFBwfvr2UPHSh951Ht93AqWNYToWQdMyMXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}