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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4463634ab041b0a3f8e7fc8aabb81e849a927e9fa8486c00e1f9f1dc426c76a0' 
  AND token = 'AnSEoBH1XphBU0TyeEo1jSrvA/UyhAYVeW2YviQrsGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}