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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea00a85c9635730dcf138737d8c6ce76ac811c9e096cd37b7f16405436b259c' 
  AND token = '4nhFLVxDale5zcGaKqt2j+OhQPFIUx0UfSBgC0q1AAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}