SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33dbeae5675684e0e386a0c6837f3f999f197d53f7e98a52775c55d418707d81' 
  AND token = '8xXqeNMKD7EfGy0cCv+KnQr3/rqm06txk9SavJZ6UAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}