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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b67bbc804b02ae92b96334daa84d2521020feb163cf105e459e26757e62d4c6' 
  AND token = 'IM6PMzJ6qmx2I9fP9/K8yGglLEGPcaFBsSzJieckZ9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}