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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022309e12d5c9ede6685eb6676175a7d0a00e688243527a99233af8cb7d22a0c' 
  AND token = 'MJvf9kRj3hUTngHfV9wpagCuHlgcCxrQ1ud8yLRxIpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}