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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7936675bb25c6722e9bed62de5ab4f703d40735a7c47a7c250b52f6dd122f63' 
  AND token = '1q70g/Mpdf2vBjV7RSPsaeOKPKVuAwcTIXCybOBCQvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}