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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '655c22b508671afd4593f5b550e36541d6b7b17cc50d8b795010e95f717e5dc6' 
  AND token = 'vDIGyKsWQgla/0aL70vj0TjSKsS5+On5IWyXuL4z8wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}