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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd45b51beb5f68c448852462986664e86d73fcc83a88f8152528e881a0a9e2633' 
  AND token = 'Q+CJmbcctV1o1qxTeLiLAccig69mp6HvWwLu+OPZ9nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}