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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48d4bed5419a59369ddb5fae66a1d0782d6b9aa564971b5714a75bfb6ae23de' 
  AND token = 'FHTH12VNj7p7MMZRnSs3yFOXf3kzXcm0PgvdV3a+sAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}