SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '841235a127a1441a5f1aaf2b2fdef1ea1b02fc8464972dcd53d1f91c5fa07588' 
  AND token = '8a1rux65eBYO+7JsoUXj7gb7BTvIh8l2iRunSpyBVFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}