SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e06daf3d0e7931aa2030acb577bfdbe6badaf1f1fa55feb03852e380b45fac84' 
  AND token = 'UmeyH4QLdiNi+kLGlBEwHNrGdU7NVdZe45ULA2mqgUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}