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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8625d808aeb3ba5dc496800bab32f4cd5a01c63dba50e3a62661049891961a36' 
  AND token = 'zUYEDZnc6tKV3fRJZ5wwLzOn+JKsc2bfnDYlTVqCLn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}