SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85c25205b7b140de6be469942206e6c2c2adfd8eeb66c76209a5d4dd8ca8a638' 
  AND token = '6F3BMMebRpzxXTwynTpkQvHqfKC5KmP3LyQ1Y7cTTlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}