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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dc737fa00386893e09f4304e950c717894e6eba4ce18077105618564f01863d' 
  AND token = '2w7iz3I5pf74XrkU5SRkRvrUdjCPkT4FA6U/NfCgAis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}