SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd80ff9b7415255095d81be98841e3647d764a9d3a3f9a335211c2f783a3d010' 
  AND token = 'feMK3kQpkcWlGljw4h0JV/u5AguoShP9FMn85XV4IQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}