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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c42806711d958d2f53e3777cbfb91cb4e3c6cd6e2983a294174a56d23ae49f72' 
  AND token = 'G6Tfd7h20mBH55TyHfFyljvocOEc/b2mP8YhxGHeAOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}