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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed592c424af45d279e0ac9e43ee19458ddb06964fd812f6542109dd997d44403' 
  AND token = '7MJyyb/3mmTikLY9OEoRzO6z/5zHUM0gbbPLx2ZjzeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}