SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2f3a6cf60aaea01b1f608ef088c96493f4825b95f127ebe16e251440be06d37' 
  AND token = '6Fq+W2XURWdKGDUthH8F0dP1YtLOkKTZ+rovu7BDWC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}