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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e41b1f14480a3d0b98fb57aeef5d0a15a31466f466a49349d88c818590b81a4' 
  AND token = 'rXB/uST4LjpgY82w7XnVQQWP3BCA4rSDWeojtNwyjjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}