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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '043ac5f3e565174ff5fbeb0c1b9acd60b696e07232b0eb84243904305ba945dc' 
  AND token = 'ZCNbMt2kmEdLcr8JwZibG8LLH3wsFw3XOMF6VJkkfQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}