SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a29f7253659b8fc6fff9550ee8ff0cea7e8686c3e24066518c3d80cb7efe245a' 
  AND token = 'lgM5HscLSK7bPK4rFUSAa7+G1XNgV7tqrZP64Rcgd9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}