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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6741f6bd79d87ff26cc8d215942bf98308022c3497dd8dc1b6b096b3a0e2e1' 
  AND token = '7yP/OC7aLZCdcOz8D0q7t5GVu8cZxPamZt8GzaJUpm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}