SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7588abc1831c69d03aaa8c744c239d79dc99ab99840546b2be8f79569cd01cd8' 
  AND token = 'lfo0wEtrQPCTL5cCqlbDfFqBmOD0NcoP1cnIcAc33uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00183

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}