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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ff0d4541a3682d8aebfadacfd955750cb01043e4657e065cdf18489de1eeea9' 
  AND token = 'BVz2TDxs+G+A7I7yLW2pnLlswe5HKY8jrrdAwqVSdUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}