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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da680acc89237f259634224b81e2846404074e305b342ac4e23079abecb2f613' 
  AND token = 'an7u8aUV6T5yMcd2KHCuR6ZnMZiW8AWEmTHIpwd5hD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}