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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88cde84a761f612ee165ae32a5da378309b4f587780a36b23d4bdf7e220bf74b' 
  AND token = 'EdESMmu73bnLk+m9f/eiQGhPXRYrK7CTESL3j95HYlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}