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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab826ee0d1c860dd34de26d29b7391b03ee7547ca8a10a9e5e54d86779016e5' 
  AND token = 'Qa8X7EZjG5psFD3PPGs47QeH8bDBfTQMm7DHZCHFaAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}