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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4003a160bca9965d231ea2da8598126a729626ba8cd8b4a8a86f10a15b1e9c81' 
  AND token = 'sf5XTpX9O1wJCdpofKMWegy6AUdjwaXp9yfh+L9GLbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}