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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0c0b3dad6764da3dc191868e75615af54c6df478eb91ad232b8d3268f72ecc4' 
  AND token = 'H3m4sd4U3U2DAJrIeTaIPoHtirXLLnei/75IVC/SWF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}