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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd19be2f8ffb5d099d50226d13e63975b0d1e0a3eb2ae3b2210f9565e2458fa63' 
  AND token = 'gehUmu2qRLtDmsltG7CdajLtSc9gB9mBEJzaK+8llVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}