SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebc1e82610bd49fa2d89256018d8972ccce7056b1ed2917f46e7de44930cbd81' 
  AND token = 'mARgdEbCG258f4DpOTrmRdCIiy3tArLYOuXeqzjiJMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}