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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7c6e1985652f97ea150c750536212cbe606bf7cf449181e49541a17e3a16be5' 
  AND token = 'WumJLSFmd5ODDBdj9X+U07z6UxZQAMXOW8ivtVxhjsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}