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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '744d634edb2cf1f71f8e05e254fdf28837b358d5c60db54089f7b8cc3b391624' 
  AND token = 'aYkmQnqnnBWJwYvuZ5q42zOwRp8J1sfkhyb6N1iNnYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}